This will be related to the recent Cyber Security Notice.
B&R products use insufficient communication encryption (br-automation.com)
The licensing of AS V4.10 is based on the Technology Guarding Tool. In the Cyber Security Notice it is mentioned that a TG Tool Version >= 1.4.0 is required now and older versions do not work anymore. I guess the Version included in the AS V4.10 installer is lower.
You can download and install the newest version of the TG tool separately. After installing the new TG version, it should work again.
Technology Guarding | B&R Industrial Automation (br-automation.com)
PS:
This should work for all AS installations >= AS V4.2.x.
AS Versions <= 4.1.x do not yet use the Technology Guarding tool as far as I know. Please contact your local sales or support team in such cases.